5 Must-Have Features in a hydrolyzed fish collagen manufacturers

Wondering about major sources of collagen? Fish collagen definitely tops the list.

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While there are benefits associated with all animal collagen sources, fish collagen peptides are known to have the best absorption and bioavailability due to their smaller particle sizes compared to other animal collagens, making them antioxidant powerhouses. Bioavailability is highly important since it largely determines the efficacy of any nutrient you ingest.

Fish collagen is absorbed up to 1.5 times more efficiently into the body and has superior bioavailability over bovine or porcine collagens. Since it's absorbed more efficiently and enters the bloodstream more quickly, it's considered the best collagen source for medicinal purposes.

Fish collagen's ability to be more easily absorbed by our bodies is thanks to its lower molecular weight and size, which allow the collagen to be absorbed at a higher level through the intestinal barrier into the bloodstream and carried throughout the body. This leads to collagen synthesis in the joint tissues, bones, skin dermis and many other essential body systems.

Since we don't tend to eat the parts of the fish containing collagen (mainly skin and scales), making homemade fish stock or supplementing with collagen is the next best thing.

What Is Fish Collagen?

Fish collagen is a complex structural protein that helps maintain the strength and flexibility of:

• skin
• ligaments
• joints
• bones
• muscles
• tendons
• blood vessels
• gums
• eyes
• nails
• hair

It's a type I collagen, which is the most abundant collagen in the human body. Type I is best known for providing the foundation for beautiful skin, strong connective tissues and sturdy bones.

Fish collagen peptides have very specific amino acid compositions with a high concentration of glycine, hydroxyproline and proline.

When fish collagen is ingested, hydroxyproline peptides are not completely digested to free amino acids and can be detected in the blood. These hydroxyproline peptides stimulate cells in the skin, joints and bones, and they lead to collagen synthesis through cell activation and growth.

The scales, skin, bones and fins of fresh or saltwater fish are used for the creation of fish collagen supplements. Since these parts are considered waste products during fish processing, using them to create other products helps reduce environmental pollution.

Health Benefits

1. Anti-Aging

Since fish collagen is a type I collagen and type I collagen is what our skin consists of, it's not surprising that it can benefit the skin. It helps prevent and improve any signs of skin aging, making it a great anti-aging food.

Possible skin benefits of consuming this collagen include improved smoothness, better moisture retention, increased suppleness and prevention of deep wrinkle formation.

Hydrolyzed fish collagen is composed of small, low molecular weight peptides, which are easily digested, absorbed and distributed by the human body.

Research published in in the Open Nutraceuticals Journal states how numerous clinical trials have now been performed showing the efficacy and benefits of collagen peptides on skin properties, including hydration, elasticity and reduction of wrinkles. Researchers conclude that hydrolyzed collagen is a smart weapon in the everyday fight against the undesirable yet visible signs of aging.

2. Bone Healing and Regeneration

Fish collagen has shown its ability to increase the body's own natural collagen production. In the past, studies have demonstrated that collagen peptides from fish skin might have a positive effect on bone health by increasing bone mineral density and exerting anti-inflammatory activity on osteoarthritis.

The goal of one study was to determine effects of fish collagen peptides on collagen synthesis, quality and mineralization. Findings of the study show that the fish collagen has a positive effect on collagen synthesis and collagen quality.

Researchers also found that the fish collagen was helpful in the matrix mineralization of bone-synthesizing cells in vitro. While this study did not involve human subjects, it does show how fish collagen is biomaterial that can aid bone healing and regeneration.

Furthermore, researchers from the NC Oral Health Institute at the University of North Carolina at Chapel Hill's School of Dentistry examined the effects of fish collagen peptides in an osteoblastic cell culture system. They found that fish collagen peptide supplementation 'exerts a positive effect on osteoblastic cells in terms of collagen synthesis, quality and mineralization, thereby suggesting the potential utility of FCP for bone tissue engineering.'

3. Wound Healing

Fish collagen might help your next scrape, scratch or more serious wound to heal better and faster. The ability of a wound to heal is ultimately based on collagen, which is essential to wound healing because it helps the body form new tissue.

Type I collagen is the most abundant structural component of the dermal matrix so it makes perfect sense that having more type I collagen in your body might help wounds to heal faster.

It was previously believed that collagens were just structural supports. Now we know that collagen and collagen-derived fragments control many cellular functions, including cell shape and differentiation, cell migration, as well as the synthesis of a number of important proteins.

Collagen also plays a critical role in all phases of wound healing: hemostasis, inflammation, proliferation and remodeling.

4. Increased Protein Intake

By consuming fish collagen, you don't just get collagen ' you get everything that collagen contains. Fish collagen is over 97 percent protein with no fat, sugars or carbohydrates, making it one of the absolute best protein foods on the planet.

It also has a very distinctive amino acid profile.

Amino acids are organic compounds that combine to form proteins. They, along with proteins, are the building blocks of our bodies.

By increasing your protein intake through consuming collagen, you can improve your workouts, avoid muscle loss (and prevent sarcopenia) and have a better recovery post-workout. More collagen protein in your diet also always helps with weight management.

5. Antibacterial Abilities

Research out of Canada published in found that fish collagen has yet another impressive component: collagencin, which is an antibacterial peptide from fish collagen. This study found that collagencin completely inhibited the growth of Staphylococcus aureus, more commonly known as staph or staph infection.

Staph is a very serious, highly contagious infection caused by bacteria commonly found on the skin or in the nose. For the future, marine collagens look like a promising source of antimicrobial peptides, which could improve both human health as well as food safety.

Nutrition

The exact nutritional content of fish collagens varies. Here's an example of a 10-gram serving of hydrolyzed fish collagen, which contains about: (9)

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• 45 calories
• 9.4 grams protein
• 0.07 milligrams potassium
• 0.05 milligrams calcium
• 0.04 milligrams iron

Fish Collagen vs. Other Types

• Bovine (cow or beef) collagen: Bovine collagen comes from cows, specifically from their skin, bones and muscles. It's made of mostly types 1 and 3 collagen, which is a good fit considering these are the most abundant types created and found in the human body. It's a rich supply of glycine and proline and therefore useful for creatine production, building muscle and also helping the body make its own collagen.
• Chicken collagen: The type of collagen most abundant in chicken collagen is type 2, which is best for building cartilage. This makes this collagen beneficial for joint health, especially since this source also provides chondroitin sulfate and glucosamine sulfate ' both of which have anti-aging effects. Most supplements containing collagen usually use chicken collagen and provide type 2.
• Fish collagen: Collagen derived from fish has been found to be easily absorbed and provide mostly type 1 collagen, with the amino acids glycine, proline and hydroxyproline. Because type 1 can be found throughout the entire body, consuming more fish collagen has been associated with benefits for the joints, skin, vital organs, blood vessels, digestion and bones. Hydroxyproline is an important component of the collagen triple helix, and lower levels have been associated with joint degradation and therefore symptoms/signs of aging. Hydroxyproline is needed for collagen stability and is created by modifying normal proline amino acids after the collagen chain is built. This reaction also requires vitamin C (to assist in the addition of oxygen), which is why vitamin C deficiency can cause abnormalities in collagen levels.
• Egg shell membrane collagen: Egg collagen, found in the shells and whites of eggs, contains mostly type 1 collagen. It also has type 3, 4 and 10, but by far the most type 1, just like the human body (approximately 100 times more type 1 than type 4). It provides glucosamine sulfate, chondroitin sulfate, hyaluronic acid and various amino acids that have benefits for building connective tissue, wound healing, building muscle mass and reducing pain/stiffness.

History

• The first time chemists extracted collagen from fish skin appears to be .
• Fish collagen is sometimes called marine collagen, but marine collagen products are sometimes sourced from shellfish and jellyfish, which I don't recommend.
• Fish collagen is sourced from the scales, skin, bones and fins of fresh or saltwater fish.
• Historically, full use of the fish body can be seen in many dishes, including the heads and eyes.
• In Chile and other parts of South America, fish heads are used in a dish called caldillo de congrio, in which the fish heads are boiled together with vegetables and herbs to make a nutrient-dense, collagen-rich stock. This is used as the base for the soup.
• Fish collagen is high in essential and non-essential amino acids.

How to Use

You can find a fish collagen supplement at your local health store or online. It's available as a pill, liquid or powder.

You should choose one that comes from a reputable company and is non-GMO and gluten-free. Also, makes sure it has no fillers, sugar, artificial flavors or artificial preservatives.

You might find hyaluronic acid and vitamin C included in your marine collagen supplement because they aid the absorption of collagen. Beware of collagen supplements made in countries with loose manufacturing controls and standards.

When collagen is hydrolyzed, the protein molecules are broken into smaller molecules. Hydrolyzed fish collagen supplements are more easily digested and absorbed by your body.

Fish collagen is different from marine collagen. Many marine collagen products are sourced from shellfish and jellyfish, which I don't recommend.

Always store collagen products in a cool, dry place.

You might be scared to buy and use fish collagen products because you think they'll smell and/or taste like fish. Not to worry ' there are many fish collagen products on the market today that are tasteless and odorless or have a neutral, non-fishy taste.

You can easily mix powdered collagen with smoothies, coffee, tea or a cup of hot water. You can even add it to soups or sauces.

Want to get your dose of fish collagen first thing in the morning? Try adding fish collagen powder to my Pumpkin Pie Oatmeal Recipe ' it's sure to start your day right!

Homemade fish stock is another great way to obtain the collagen benefits of fish. Try a Homemade Fishstock Recipe (wine optional) loaded with collagen and other health-promoting nutrients, along with other fish bone broth recipes.

In addition to adding a fish collagen product to your diet, you can also get this tremendous protein through collagen supplementation, such as collagen hydrolysates. Collagen hydrolysate supplements are easy to find at most health food stores or pharmacies.

Risks and Side Effects

There are no commonly reported side effects of fish collagen.

Final Thoughts

With more than 40 years of experience, TCI has imported and exported to more than 63 countries and has more than 1,124 partners worldwide. TCI is a trusted private/white label manufacturer and is a global supplement and skin care product supplier.

TCI has its own research and development capabilities and cooperates with medical institutions to conduct clinical tests. We provide clinical test reports to our customers to guarantee the effectiveness of private label collagen products and help them in the global health and nutrition market.

Recently, research has found that collagen supplements 'replenish the loss of collagen,' and deliver special dipeptide components from collagen: proline-hydroxyproline (Pro-Hyp). This ingredient has the 'signal transduction factor' function.  After absorption, it may promote the proliferation of human skin cells, synthesize collagen, stimulate the activity of hyaluronic acid enzymes, and increase hyaluronic acid content in the human skin. The formation process of collagen in the human body is extremely complex. To form collagen, each tissue needs to have enough amino acid raw materials, and various polypeptide precursors to drive the action of fibroblasts.

 In , Professor Kenji Sato of Kyoto University found that if hydrolyzed collagen is ingested, the concentration of dipeptide molecules greatly increases in the blood [1]. Animal experiments at Tohoku University in Japan fed mice with isotope-labeled small molecule collagen. The results also detected the collagen signals in the blood, indicating that the absorption rate of collagen can be significantly increased with post-treatment collagen [2].  Another study found that after feeding pre-treated collagen, the signals of these collagens could be detected in the skin, bones, and joints of experimental animals [3,4], Thus, indicating that not only can the pre-treated collagen be absorbed, but it can also be distributed to the skin, joints, and other tissues. This provides some Pharmacokinetic scientific evidence for the efficacy of collagen.

Collagen offers plenty of health and beauty benefits, making it popular among consumers. Potential benefits of using skincare and wellness products that contain collagen are:

• Smooth skin
• Stronger nails
• Improved joint health
• Lean muscle mass
• Shiny hair
• Better skin elasticity
• Improved density of the bones

The effect collagen has, specifically on the hair, skin and nails makes it desirable to consumers striving for long-lasting results from their beauty products. A Consumer Reports survey found that 7% of American men and 19% of American women have used collagen in the past. The role of glycine in collagen is that it's 1 of 3 amino acids producing glutathione. This powerful antioxidant prevents damage to the cells caused by free radicals.

The research and development team at TCI used two-stage scientific verification (picture). The efficacy of collagen cells and clinical trials were confirmed in the first stage. After the efficacy was confirmed, the active function analysis was carried out during the second stage. First, fast protein liquid chromatography (FPLC) and high performance liquid chromatography (HPLC) were performed to purify and separate collagen. Then, a high-resolution mass spectrometer (Q-Tof MS) was used to analyze a complete composition map and amino acid sequence structure of collagen. In addition, biological databases (UniPro, PDG, ExPASy and PubMed, etc.) were used to interpret a large amount of data to unlock the secrets of collagen peptides. Through scientific verification by the research and development team of TCI's Molecular Identification & Analysis Laboratory (MIA Lab), they were able to analyze the types of collagens from different sources, amino acid sequences, special functions and active structural regions of various collagen peptides to create unique functions for various collagens. Thus, TCI was able to provide more complete and professional information to the customer so that they are no longer confused by the different collagen products in the market.

If your brand is aiming for growth in nutritional supplements, collagen may be a good fit for you. With beauty and wellness products, consumers are looking for three key elements that make them take action and close a deal:

• Sustainability
• Traceability
• Clear benefits

For your collagen product to sell, you must appeal to the ethically minded consumer in the wellness space who wants reassurance that your product meets their standards. It means using your labeling to communicate how you source your materials, where you manufacture your product, where you get the ingredients and what those are. You also need to define the product's advantages to show the customer why they need it now.

With collagen, there are plenty of perks that make this possible. Using private labeling through a company like us, TCI makes it easy to show consumers why your collagen product is worth choosing.

We also have introduced a new vegan alternative collagen VeCollal® and have developed various health supplement products that are animal-free, with low carbon emissions, and sustainable. If these are your company's priorities, we can create supplements for you. The plant-based movement is growing, and consumers are interested in vegan alternatives for supplements. Get a quote on VeCollal® for your company today.

There are many benefits of private labeling for your brand. Private labels refer to a label that your corporation owns, displaying the brand name. An excellent example of this is Costco's brand "Kirkland." When you add a private label to a product sold at your store, you claim accountability for the quality and reassure customers about what they're buying.

There are many reasons to consider this labeling option for your products. At TCI, we can help you make this dream a reality with 40 years of proven experience in helping our clients take products from concept to launch. We help you make a profit through consultation, quality management, manufacturing, product planning and more.

Don't miss out on the advantages of private labeling for collagen or other wellness products. These include:

1. Higher Profit Margins
When you sell your products under a private label, you're saving money on marketing costs (that would be paid to a premium brand for their name). You also get the product from the manufacturer for what it's worth, rather than paying extra because of the name on the label.

2. Reduced Operating Costs
Your operating costs are lower for private label products because you don't need to spend money on marketing campaigns. The skin, body, vitamin food, or diet products you sell under a private label should be items that sell regularly and don't require promotion to be desirable. Then, your private label speaks for itself. It's also produced in high quantities by the manufacturer, allowing them to lower the cost.

3. Brand Loyalty
A private label works to your advantage because consumers who trust your brand and shop with you regularly also develop respect for your private label products. Whether vitamin C, oral collagen supplements, or other collagen products, they'll choose your private brand product (and its lower price) over a premium brand-name product.

The company is the world’s best fish collagen manufacturer supplier. We are your one-stop shop for all needs. Our staff are highly-specialized and will help you find the product you need.